Moderate Glucose Control Is Associated With Increased Mortality Compared With Tight Glucose Control in Critically Ill Patients Without Diabetes
نویسندگان
چکیده
منابع مشابه
Tight blood glucose control is renoprotective in critically ill patients.
Two large, prospective, randomized, controlled trials have shown a beneficial effect of intensive insulin therapy (IIT) on the kidney function of critically ill patients. The data from these trials were combined for performance of a more detailed analysis of the renoprotective effect of IIT. After exclusion of 41 patients with preadmission ESRD, the study sample comprised 2707 critically ill pa...
متن کاملGlucose control and mortality in critically ill patients.
CONTEXT Hyperglycemia is common in critically ill patients, even in those without diabetes mellitus. Aggressive glycemic control may reduce mortality in this population. However, the relationship between mortality, the control of hyperglycemia, and the administration of exogenous insulin is unclear. OBJECTIVE To determine whether blood glucose level or quantity of insulin administered is asso...
متن کاملTight glucose control in critically ill patients: should glucose meters be used?
Measurement of blood glucose concentrations using portable, hand-held meters is used widely in patients with diabetes. Clinical settings include self-monitoring of blood glucose by patients, in doctors’ offices, in chronic care facilities, and in hospitals. More recently, evidence has emerged suggesting that tight glycemic control of nondiabetic patients in hospital intensive care units (ICUs) ...
متن کاملBlood glucose control among critically ill patients with brain injury.
OBJECTIVE To evaluate the incidence of hypoglycemia, hyperglycemia and blood glucose (BG) variability in brain-injured patients and their association with clinical outcomes. METHODS Retrospective cohort study of brain-injured patients admitted to an 11-bed neurosciences intensive care unit (ICU) from January 1 to December 31, 2003. RESULTS We included 606 patients. Mean age was 52.3 years, ...
متن کاملCoefficient of glucose variation is independently associated with mortality in critically ill patients receiving intravenous insulin
INTRODUCTION Both patient- and context-specific factors may explain the conflicting evidence regarding glucose control in critically ill patients. Blood glucose variability appears to correlate with mortality, but this variability may be an indicator of disease severity, rather than an independent predictor of mortality. We assessed blood glucose coefficient of variation as an independent predi...
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ژورنال
عنوان ژورنال: Chest
سال: 2013
ISSN: 0012-3692
DOI: 10.1378/chest.12-2072